DrugBank does not market nor buy medicines. Pricing facts is supplied for informational purposes only.apalutamide will lower the level or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with medicines which have been CYP2C19 substrates m